IVF with In vitro maturation (IVM)
Home / IVF with In Vitro Maturation (IVM)
In conventional IVF treatment, eggs are collected from the ovaries when they are fully matured. Using the technique of
in vitro maturation, fertility clinics harvest eggs before they have matured and allow the eggs to mature 'in vitro' or outside of the body. This technique prevents problems associated with fertility drug use, such as ovarian hyperstimulation syndrome, reduces the cost of IVF treatment cycles as fertility medication is not needed and offers a higher success rate than natural cycle IVF.
Procedure for IVF with IVM
An ultrasound is performed between day 3-5 of the woman's menstrual cycle to check there is a sufficient number of follicles for harvesting. 36 hours before the eggs are to be harvested, an injection of the natural hormone HCG (human chorionic gonadotropin) is given to mature the eggs before they are collected.
Once the eggs have been collected, healthy eggs are matured (cultured) in a laboratory for up to 48 hours. The mature eggs are then fertilized using conventional IVF or IVF with ICSI methods before being transferred back into the womb.
Benefits of In Vitro Maturation
- In vitro maturation provides a safe alternative to stimulated IVF for women who are at high risk of ovarian hyperstimulation syndrome (OHSS).
- Women with polycystic ovaries are highly likely to conceive using this method of egg collection. Compared to the average 4 eggs produced by women with a normal menstrual cycle, women with polycystic ovaries produce around 16 eggs per cycle.
- Reduced cost of IVF treatment due to no fertility drugs
- IVM can offer a fertility preservation method to young women with an illness likely to damage fertility as immature eggs can be harvested, matured in vitro and then frozen for later use.
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