Through the advancement in technology and the development of single embryo transfer, our team is able to do is select a single, robust embryo to utilize during insemination. By doing so, infertility specialists in Turkey can maximize your likelihood of conception and having a healthy delivery while minimizing the risk of multiple pregnancies.
Prior to recent breakthroughs with blastocyst transfer, embryos conceived through in-vitro fertilization (IVF) were typically transferred to the woman’s uterus on the third day after fertilization.
Blastocyst transfer, the transfer of embryos on the fifth day after fertilization, helps infertility clinics in Turkey to maintain the high pregnancy rates that patients have come to expect while decreasing the risk of multiple gestational pregnancies.
Embryo Transfer using Frozen Embryo
Embryo freezing or cryopreservation, is a method that cryopreserves embryos for future use. During IVF cycles, more embryos are produced than the maximum number of embryos that can be transferred in one cycle.
It is possible for couples to freeze their healthy excess embryos for further IVF treatments, or can donate the embryos for use by infertile couples. Infertile couples who choose to use donated embryos in IVF treatment cycles are matched with embryos from couples whose physical and emotional attributes match those of the recipient couple.
Frozen Embryo Transfer Cycle
Before frozen embryos can be inseminated into the recipient’s uterus, the embryos must be thawed until the outside temperature of the egg matches the temperature of the uterine lining. Once thawed, the procedure for using cryopreserved embryos in IVF treatment cycles is identical to using embryos which have not been cryopreserved. The embryo is inserted into a catheter which is passed into the uterus through the vaginal passage. The implantation of embryos is performed on the optimum day for successful implantation into the uterus.
Women who are at risk of developing ovarian hyperstimulation syndrome(OHSS), following ovarian stimulation for IVF treatment using fertility drugs, are advised to freeze all successful embryos for consecutive embryo transfer in repeated IVF treatment cycles. Couples who are infertile as a result of unexplained fertility, male infertility or female factor infertility can successfully conceive using frozen embryos.
Embryo Freezing Method
Embryo cells contain water which must be removed prior to freezing so as to prevent ice crystal formation. The embryos are then mixed with a cryoprotectant fluid, and put into a glass ampoule. They are stored in liquid nitrogen at a low temperature where they remain until used.
Embryo Thawing Method
To thaw frozen embryos, they are removed from the ampoule and brought to room temperature. The cryoprotectant fluid is gradually removed and carefully diluted with water. When the embryos are fully returned to the temperature of the recipient uterus, they are transferred to the recipient mother.
Difference between Embryo Transfer and Blastocyst Transfer
The difference between embryo transfer and blastocyst transfer is the timing – embryo transfer is performed 2-3 days after fertilization when the cells are still dividing. Blastocyst transfers are performed 5-6 days after fertilization to increase the chance of successful implantation.
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